Found 12 matching trials
Combination Osilodrostat and Cabergoline in Cushing's Disease
PHASE4Cushing disease remains a challenging endocrine disorder in which persisten...
Status
Enrolling By Invitation
Location
Faiha Specialized Diabetes, Endocrine, and Metabolism Center
Safety and Efficacy of LCI699 in Cushing's Disease Patients
PHASE2This exploratory study is a proof of concept study to determine whether LCI...
Location
Northwestern University Endo, Metabolism and Molecular
Efficacy and Safety Evaluation of Osilodrostat in Cushing's Disease
PHASE3The purpose of this study was to confirm efficacy and safety of osilodrosta...
Location
University of Colorado Endocrinology Clinical Trials Unit
A Study to Evaluate the Efficacy and Safety of LCI699 Compared to Placebo in Participants With Resistant Hypertension
PHASE2This study assessed the blood pressure effect, safety and tolerability of L...
Location
Horizon Research Group, Inc
Osilodrostat in Patients With Hypertension Caused by Hypercortisolaemia Due to Cushing's Syndrome
PHASE4Osilodrostat has proven to be a safe and efficacious treatment for patients...
Location
Multiple Locations
Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS)
PHASE4This study will compare the efficacy and safety of the two 11β-hydroxylase ...
Location
Laikon General Hospital
Safety and Efficacy of LCI699 for the Treatment of Patients With Cushing's Disease
PHASE3The study aimed to confirm long-term efficacy and safety of LCI699 for the ...
Location
University of Colorado Hospital SC - LCI699C2301
Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome
PHASE2Multicenter, open-label, non-comparative study to evaluate the pharmacokine...
Location
University of California San Francisco UCSF
A Phase I Study of Osilodrostat (LCI699) in Healthy Volunteers and Subjects With Impaired Renal Function
PHASE1To characterize the pharmacokinetics of LCI699 following a single oral dose...
Location
Novartis Investigative Site
Impact of 1 mg Osilodrostat Therapy on Mild Autonomous Cortisol Secretion (MACS)
PHASE2The purpose of this study is to evaluate the safety and tolerability of 1 m...